The response of the enzymatic feedback system to an oscillatory input was studied in order to characterize the model system with emphasizing specially the qualitative difference in response of the system from that of a linear feedback system. The frequency response-curve of the enzymatic feedback system exhibits single or double peaks and the positions of these peaks in the frequency axis shift as the feedback constant increases. The distorted wave form on the reactant concentration is observable only in the case that the input had a low frequency or low angular velocity. The stationary value of the end product changed scarcely against the ω value of the input except for the input with a certain value of angular velocity which causes a peak in the frequency response-curve. The frequency of the input is held almost invariably through the oscillations of the reactants in the system.
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