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Blood Dioxin Concentrations and their Tendencies Examined in 2001-2017 Annual Inspections for Yusho
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| Abstract | We performed congener specific analysis of dioxins using HRGC/HRMS and determined their concentrations in blood samples collected from approx. 1,700 persons during annual Yusho examinations between 20...01 and 2017. When concentration of 2,3,4,7,8-pentachlorodibenzofuran (PeCDF) was compared in seven Yusho patients undergoing examinations among the seventeen years, the longitudinal concentrations in the respective individuals hardly changed over these years. Mean concentration of 2,3,4,7,8-PeCDF in blood from Yusho patients registered by annual inspections for Yusho was calculated as 110 pg/g, which was 80％ higher than the mean value of 17 pg/g in normal controls, and the rates of persons with blood 2,3,4,7,8-PeCDF concentrations below 50 pg/g in the entire patients occupied approx. 60％. On the other hand, in a subset of Yusho patients registered by the supplemental criteria revised on 2012, it was found that the median values of concentration of 2,3,4,7,8-PeCDF were similar to the those of normal controls.show more |
| Table of Contents | はじめに 実験方法 結果及び考察 総括 |
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| Created Date | 2019.07.22 |
| Modified Date | 2023.11.14 |