||Plate (or slope) cultures of cerulomycin-producing Streptomyces coerulescens (KCC S-0360) showd spontaneously develping pocks which increased in number during subculturings. No spore formation and red...uced aerial hyphae formation were observed in the pocks, whereas the formation of substrate hyphae were not inhibited. Almost all of the hyphae were broken or lysed in the pocks, and many phage tail-like particles, containing long tail type and bullet-shaped type, were observed in the pocks. The bullet-Shaped particles often formed a hexagonal crystal. No activity of self-replication was associated with the particles. The production or these particles did not occur in the liquid culture and the young or normal plate culture having no pocks. These results were similar to those of thiostrepton-producing Streptomyces azureus (ATCC 14921) and endomycin-producing Streptomyces endus (KCC S-0213), which have been described previously.
1.抗生物質cerulomycin生産性のStreptomyces coerulescens(KCC S-0360)は外来性ファージの感染によらず内的要因によって固体培地上に継代培養ごとに数が増大するpockを生じながら菌叢を形成した.2.Pock中の大部分の気中菌糸及び胞子着生菌糸は溶菌していた.3.Pock中には,ファージの尾部先端構成成分に類似した粒子が,溶解した菌糸の周囲や内部に多数存在していた.4.気中菌糸と胞子首生菌糸の溶解とファージ尾部様粒子の存在は,これまで報告してきたthiostrepton生産性のStreptomyces azureus(ATCC 14921)とendomycin生産性のStreptomyces endus(KCC S-0213)のpock形成現象と非常によく類似していた.続きを見る