White Leghorn male chicks of 60 and 90 days of age were intramuscularly injected each other day with diethylstilbestrol (DES) at levels of 0.1, 0.5 and 1.0 mg for 20 to 140 days, as already reported in detail in my previous report. Some biochemical effects of DES on the liver and blood of those chicks were studied and the following results were obtained. 1. Activities of succinoxidase, succinic dehydrogenase, tyramine oxidase, choline oxidase and esterase of the liver and phosphatase of the blood showed no marked change with the DES injection. It showed some decreasing tendency of activity of alkaline phosphatase in the liver. 2. Concentration of serum PBI of the c hicks was not altered noticeably with the DES injection. 3. Concentration of blood glucose showed no change, and that of acetone bodies showed some variable results in serum of the chicks injected with DES. 4. Concentration of vitamins A and B2 in the liver, kidney and muscle varied slightly. It appeared to increase them in some degree in the tissues of the chicks injected on high level of the hormone.
Mendeley出力
