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Although previous studies have suggested that salivary alpha-amylase (sAMY) reflects sympathetic nervous activity and is a useful stress-related biomarker, the relationship between psychosocial factor...s, lifestyle factors and sAMY activity has scarcely been investigated in large samples in an occupational setting. A total of 227 office workers were examined by a hand-held monitor (Amylase monitor, Nipro Co., Ltd.) in the morning during annual health checkups to find whether sAMY activity was associated with psychosocial factors such as : Type A behavioral pattern; several kinds of mood , including depression; general health status; and fatigue. The device was developed as a rapid and easy-to -use analytical tool for the measurement of sAMY activity. Physical activity and several lifestyle factors, such as smoking, drinking, and dietary behaviors were also investigated in relation to the sAMY activity. The sAMY activity was not associated with the time course of 3-hour investigation in the morning. The Type A scale showed a tendency of a positive correlation with sAMY activity. Intake of breakfast was also relatively related to an increase in sAMY activity. Other psychosocial and lifestyle factors were unrelated to sAMY activity. Workload before measuring sAMY activity and inter-individual differences in the reactivity of sAMY might have affected the results. The present study, however, seemed to support the previous findings that Type A behavior pattern has an impact on sympathetic nervous activity. Such behavior may play a role not only in cardiovascular function, but also in salivary function.続きを見る
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