Expression Responses of the Complement Components in Zebrafish Organs after Stimulation with Poly I:C, Mimicry of Viral Infection - 九大コレクション

＜紀要論文＞
Expression Responses of the Complement Components in Zebrafish Organs after Stimulation with Poly I:C, Mimicry of Viral Infection

作成者	作成者名 Vo, Kha Tam 所属機関所属機関名 Laboratory of Marine Biochemistry, Division of Marine Biological Chemistry, Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Science, Kyushu University
	著者識別子 L004763 作成者名 Tsujikura, Masakazu 辻倉, 正和所属機関所属機関名 Laboratory of Marine Biochemistry, Division of Marine Biological Chemistry, Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Science, Kyushu University 九州大学生物資源環境科学府生物機能科学専攻海洋生命化学講座水族生化学研究室
	著者識別子 K002663 作成者名 Somamoto, Tomonori 杣元, 智軌所属機関所属機関名 Laboratory of Marine Biochemistry, Division of Marine Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University 九州大学大学院農学研究院生物機能科学部門海洋生命化学講座水族生化学研究室
	作成者名 Nakano, Miki 中野, 実樹所属機関所属機関名 Laboratory of Marine Biochemistry, Division of Marine Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University
本文言語	英語
出版者	Faculty of Agriculture, Kyushu University
出版者	九州大学大学院農学研究院
発行日	2009-10-29
収録物名	九州大学大学院農学研究院紀要
巻	54
号	2
開始ページ	389
終了ページ	395
出版タイプ	Version of Record
アクセス権	open access
Crossref DOI	https://doi.org/10.5109/16120
関連DOI	Journal of the Faculty of Agriculture, Kyushu University \|\| 54(2) \|\| p389-395
	九州大学大学院農学研究院紀要 \|\| 54(2) \|\| p389-395
	http://www.agr.kyushu-u.ac.jp/
関連URI	Journal of the Faculty of Agriculture, Kyushu University \|\| 54(2) \|\| p389-395
	九州大学大学院農学研究院紀要 \|\| 54(2) \|\| p389-395
	http://www.agr.kyushu-u.ac.jp/
関連情報	Journal of the Faculty of Agriculture, Kyushu University \|\| 54(2) \|\| p389-395
	九州大学大学院農学研究院紀要 \|\| 54(2) \|\| p389-395
	http://www.agr.kyushu-u.ac.jp/

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PISSN	0023-6152
NCID	AA00697606
レコードID	16120
査読有無	査読無
ISSN	0023-6152
NCID	AA00697606
注記	Defensive roles of the complement system in fish are largely unknown, although expressions of several complement components have been examined in some teleost species upon bacterial and parasitic infections. To infer possible anti-virus defensive roles of the complement system in teleost, zebrafish were simulated by intraperitoneal injection of poly I: C, a double strand RNA analogue, to mimic viral infection, and expression of 24 complement components and their subunits in the gill, brain, kidney, gut, hepatopancreas, gonad, heart, spleen, and skin were analyzed by reverse-transcription PCR. In normal (unstimulated) fish, the hepatopancreas showed highest expression of most genes tested, and considerable extra hepatic expression was also observed for many complement components. Upon stimulation, the hepatopancreas showed decreased expression of CD11/CD18, B/C2-A3, MASP3, and properdin, while marked up-regulation of several complement component genes was observed in the gill, suggesting an important but unknown role of the gill in host defense against viral infection.
登録日	2010.01.08
更新日	2022.11.11

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＜紀要論文＞ Expression Responses of the Complement Components in Zebrafish Organs after Stimulation with Poly I:C, Mimicry of Viral Infection

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＜紀要論文＞
Expression Responses of the Complement Components in Zebrafish Organs after Stimulation with Poly I:C, Mimicry of Viral Infection