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Handbook of Neurotoxicity

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概要 The Handbook of Neurotoxicity is a reference source for identifying, characterizing, instructing on use, and describing outcomes of neurotoxin treatments - to understand mechanisms associated with tox...in use; to project outcomes of neurotoxin treatments; to gauge neurotoxins as predictors of events leading to neurodegenerative disorders and as aids to rational use of neurotoxins to model disease entities. Neuroprotection is approached in different manners includingthose 1) afforded by therapeutic agents - clinical and preclinical; or 2) by non-drug means, such as exercise. The amorphous term 'neurotoxin' is discussed in terms of the possible eventuality of a neuroprotectant producing an outcome of excess neuronal survival and a behavioral spectrum that might produce a dysfunction - akin to a neurotoxin's effect. The Handbook of Neurotoxicity is thus an instructive and valuable guide towards understanding the role of neurotoxins/neurotoxicity in the expansive field of Neuroscience, and is an indispensable tool for laboratory investigators, neuroscientists, and clinical researchers.続きを見る
目次 Glutamate as a Neurotoxin,- Methamphetamine and MDMA neurotoxicity: Biochemical and molecular mechanisms
Microglia: Neuroprotective and Neurodestructive Properties
Neuroprotection in Demyelinating Diseases: the therapeutic potential of the neurotrophins
Neurotrophic Factors and Ethanol Neurotoxicity
Neurotrophic factors and NeuroAIDS: a lesson from brain-derived neurotrophic factor
Neurotrophins and p75NTR in axonal regeneration and myelination
Neurotrophins and pain
Neurotrophin signalling in Cancer
NGF and immune regulation
NGF/P75 in cell cycle and tetraploidy
P75 in neuronal death
p75NTR processing and signaling: functional role
p75NTR-A molecule with multiple functions in amyloid-beta metabolism and neurotoxicity
RCSN Cell System for Identifying Dopaminergic Neurotoxicity
Seizures tip the balance of neurotrophin signaling towards neuronal death
Survey of Selective Neurotoxins
Synthesis, trafficking and release of bdnf
The Nature of DSP-4-Induced Neurotoxicity
Trafficking of neurotrophins and their receptors and pathological significance
TRPV1 activators ("vanilloids") as neurotoxins
Experimental Approach to Alzheimer Disease
Iron-induced dopaminergic cell death in vivo as a model of Parkinsonś disease
Molecular, cellular and behavioural effects produced by perinatal asphyxia: protection by poly (ADP-ribose) polymerase 1 (PARP-1) inhibition
MPTP: advances from an evergreen neurotoxin
Multifunctional compounds for Parkinsons disease and Alzheimers disease
Nanomedicines for Nervous System Diseases
Neurodegenerative aspects of multiple system atrophy
Neurotoxic profiles of designer-drugs
Pathophysiology of obsessive-compulsive disorder: Insights from normal function and neurotoxic effects of drugs, infection and brain injury
Physical Exercise as Intervention in Parkinsonism
Protective agents in Parkinsonś disease: caffeine and adenosine A2A receptor antagonists
Stem Cell Therapies for Age Associated Neurodegeneration
AIDS
Excitotoxicity and axon degeneration
Glutamate Neurotoxicity related to Energy Failure
Neuroprotection by Kynurenine Metabolites
Pain
Quinolinate and related excitotoxins: mechanisms of neurotoxicity and disease relevance
Role of Ionotropic Glutamate Receptors in Neurodegenerative and Other Disorders
Tardive Dyskinesia: Outcome of antipsychotic treatment and brain damage?
The Concept of Excitotoxicity via Glu-R
The pathogenesis of Alzheimers disease
5,6- and 5,7-Dihydroxytryptamines as Serotoninergic Neurotoxins
Neurotoxicity of Methamphetamine
Neurotoxic Effects, Mechanisms and Outcome of 192-IgG Saporin
Neurotrophic therapy for ALS/ MND
Cancer-mediated neurotoxicity
Neurotoxicity in psychostimulant and opiate addiction
Excitotoxicity in HIV associated neurocognitive disorders
Necroptosis, a potential therapeutic target for neurological disorders
Epilepsy
Excitotoxicity and Amyotrophic Lateral Sclerosis
Excitotoxicity in the Pathogenesis of Autism
Glutamate Neurotoxicity, Transport and Alternate Splicing of Transporters
Glutamatergic receptors in Parkinson`s disease
Ionotropic Receptors in the Central Nervous System and Neurodegenerative Disease
Lead & excitotoxicity
Molecular Mechanism and Effects of Clostridial Neurotoxins
MS & excitotoxicity
Neuroprotectants Targeting NMDA Receptor Signaling
Neurotoxicity and ALS: Insights into Pathogenesis
Schizophrenia
Neurotoxic Vulnerability Underlying Schizophrenia Spectrum Disorders
Glutamate in the Pathogenesis of Gliomas
Neurotoxicity and Neuroprotection in Spinal Cord Injury
Drug Abuse Neurotoxicity: Alcohol and Nicotine as Developmental Stressors
Botulinum neurotoxins as therapeutics
MPTP Neurotoxicity: Actions, Mechanisms and Animal Modeling of Parkinsons disease
Endogenous Kynurenic acid and Neurotoxicity
The potential therapeutic effects of statins in Alzheimer's disease
Drug Treatments for Alzheimerś Disease: Hopes and Challenges
Glutamate and Neurodegeneration in the Retina
Stroke
Brain trauma Neuroprotection
Neuroprotective Strategies in Amyotrophic Lateral Sclerosis: Modulation of Neurotransmittory and Neurotrophic Input to Motor Neurons
The role of Neurotoxicity in Depression
Advances in stem cell research for Parkinson disease
Neurotoxicity in Huntington Disease
Fusion Models and F́usioning`in Parkinsonism: Protection and Restoration by Exercise
Neurotoxicity: a complex multistage process involving different mechanisms.
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本文を見る Full text available from Springer Biomedical and Life Sciences eBooks 2014 English/International

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登録日 2020.06.27
更新日 2020.06.28