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Glycobiology of the Nervous System

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概要 A thorough introduction is provided to the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic information as well as the latest developments in neu...ral glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. The breadth and depth of topics covered make it an essential reference for those new to the field as well more seasoned investigators.続きを見る
目次 Introduction to the Complexity of Cell Surface and Tissue Matrix Glycoconjugates
Introduction to Cells Comprising the Nervous System
Synthesis, Processing, and Function of N-glycans in N-glycoproteins
Synthesis of O-linked Glycoconjugates in the Nervous System
Chemistry and Function of Glycosaminoglycans in the Nervous System
Use of Glycan-targeted Antibodies/Lectins to Study the Expression/Function of Glycosyltransferases in the Nervous System
From Mass Spectrometry-based Glycosylation Analysis to Glycomics and Glycoproteomic
Structural Analysis of Oligosaccharides and Glycoconjugates using NMR
Glycolipid and Glycoprotein Expression During Neural Development
Gangliosides and Cell Surface Ganglioside Glycohydrolases in the Nervous System
Role of Myelin-Associated Glycoprotein (Siglec-4a) in the Nervous System
Role of Galactosylceramide and Sulfatide in Oligodendrocytes and CNS Myelin: Formation of a Glycosynapse
Glycosignaling - A General Review
Glycosphingolipids in the Regulation of the Nervous System
Glycobiology of Ion Transport in the Nervous System
O-GlcNAcylation of Neuronal Proteins: Roles in Neuronal Functions and in Neurodegeneration
N-glycosylation in Regulation of the Nervous System
Roles of Carbohydrates in the Interaction of Pathogens with Neural Cells
Glycoconjugate Changes in Aging and Age-related Diseases
Gangliosides and Glycolipids in Neurodegenerative Disorders
Glycosidases: Inborn Errors of Glycosphingolipid Catabolism
Ganglioside Storage Diseases: On the Road to Management
Dynamic Aspects of Neural Tumor Gangliosides
Galectins and Neuroinflammation
Glycoconjugates and Neuroimmunological Diseases.
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本文を見る Full text available from Springer Biomedical and Life Sciences eBooks 2014 English/International

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登録日 2020.06.27
更新日 2020.06.28