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In 1996, a total of 928 serum samples were collected from 453 males and 475 females (age from 20 to 93 years old) in two villages, Bhadrakali and Kotyang, in Nepal. These serum samples were tested for... the presence of anti Helicobacter pylori (H. pylori) IgG antibody using an Enzyme Linked Immunosorbent Assay. The prevalence of H. pylori infection was then evaluated in relation to the level of education which is one measure of the socioeconomic level. The education level was divided into four groups, depending on the highest grade of school attended: no formal education designated as "illiterate", the primary school educated group as "primary", the junoir high school educated group as "junior", and the secondary school educated (or higher) group as "secondary ". The overall prevalence of infection in the pre sent study was 60.7% and the prevalence of infection increased with age. No significant difference in prevalence was found based on gender. Comparing the two villages, the prevalence of H. pylori infection in Bhadrakali was significantly higher than that in Kotyang (69.2% vs 46.9%, p＜0.05). The level of education was inversely related to the prevalence of H. pylori infection only in Bhadrakali, but not in Kotyang. In Kotyang, although 76% of the residents belonged to the "illiterate" group, the rate of infection was lower than for the "secondary" group in Bhadrakali (48.3% vs 59.6%). These findings tend to suggest that a higher socioeconomic status appears to reduce the risk of H. pylori infection in some societies, but not in an isolated rural region such as Kotyang.続きを見る
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