<紀要論文>
運動による循環白血球数増多とG-CSFとの関係

作成者
本文言語
出版者
発行日
収録物名
開始ページ
終了ページ
出版タイプ
アクセス権
JaLC DOI
関連DOI
関連URI
関連情報
概要 We studied the relation of serum granulocyte colony-stimulating factor (G-CSF) and leukocytosis during exercise. Eleven healthy subjects were given graded exercise by treadmill. Complete blood cell co...unts. G-CSF, plasma adrenaline (Ad), plasma noradrenaline (NA), lactate, blood sugar (BS), serum sodium (Na), serum potassium (K) were determined before and during exercise. Heart rate (HR) and blood pressure (BP) were monitored during exercise. The results were as follows: 1) White blood cells (WBC) markedly increased without the significant change of G-CSF. Moderate exercise induced the increase of granulocyte and lymphocyte number while heavy exercise caused the higher rate of increased in lymphocyte than in granulocyte. 2) Hematocrit (Ht) showed significant increase during exercise although both red blood cells (RBC) and hemoglobine (Hb) hardly changed. The rate of increase in Ht was lower than that of WBC. 3) Exercise induced the increase of catecholamine, resulting in the increases of HR, BP and K. These results show that exercise-induced leukocytosis is independent on G-CSF. It is suggested that exercise induced catecholamine causes the increase of both β2-adrenoreceptor density and adrenergic responsiveness of leukocyte, resulting in leukocytosis followed by the increase of lymphocyte.続きを見る

本文ファイル

pdf 013_p035 pdf 530 KB 139  

詳細

レコードID
査読有無
地域
ISSN
NCID
タイプ
時代・年代
登録日 2009.09.10
更新日 2022.04.28

この資料を見た人はこんな資料も見ています