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尿中クレアチニン排泄量予測値と起床後2回目のスポット尿を用いた24時間尿中ナトリウムならびにカリウム排泄量の推定法

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概要 The purpose of this study is to estimate 24-hour sodium (24HUNaV) or potassium (24HUKV) excretion in urine from predicted value (PRCr) of 24-hour creatinine excretiom in urine (24HUCrV) and Na/Cr or K.../Cr ratio for the second morning voiding urine (SMVU-Na/Cr or SMVU-K/Cr). Equation for predicting 24HUCrV from age, body weight and body height was developed by the method of forward stepwise regression analysis, based on the data for the average 24HUCrV determined by 24-hour urine collected from 487 clinically healthy subjects for at least 3 days. These procedures have already been described in detail, elsewhere. One hundred and fifty-nine clinically healthy subjects (78 men and 81 women, 19-77 years of age) were studied to estimate 24HUNaV and 24HUKV. Twentyfour-hour urine and SMVU, before breakfast, were collected separately for 3 to 4 days. Values calculated from the form SMVU-Na(or K)/Cr×PRCr were closely correlated with measured 24HUNaV or 24HUKV, respectively. The estimated values for 24HUNaV(YNa) and 24HUKV(YK) were obtained the following equations: YNa=16.3√XNa, XNa=SMVU-Na/Cr×PRCr; YK=7.2,√XK, XK=SMVU-K/Cr×PRCr. The correlation coefficient between YNa(or YX) and 24HUNaV(or 24HUKV) was 0.73 (or 0.78), respectively. SMVU as well as the blood sampling before breakfast is worth using as the screening test for several diseases on the epidemiological survey. It is thought SMVU will be used widely not only for the screening test for diseases but also for estimating 24HUNaV and 24HUKV on the extensive epidemiological survey. (Journal of Health Science Kyushu University, 10: 115-120, 1988)続きを見る

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登録日 2009.09.10
更新日 2018.06.12