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Three hundred and fifty-seven subjects, 183 males and 174 females, living in a small island, Takashima, were investigated. They were mainly in their thirties and most of them were normotensive. Border...line hypertensives were highest in body weight, percent fat ratio, uric acid γ-glutamyl transferase (γ-GTP), total cholesterol. Blood pressure increased with age, and which correlated with blood urea nitrogen, serum creatinine, COT, blood glucose and total cholesterol concentration. Blood pressure elevation with age seemed to be due to impairment of renal function, hepatic function, carbohydrate and lipids metabolism with aging. Systolic and diastolic blood pressures positively correlated with pulse rate, suggesting that hypertension in younger subjects involves enhanced synpathetic nervous activity. Blood pressures were significantly positively correlated withγ-GTP, uric acid, blood glucose, total cholesterol in men, and with body weight, percent fat ratio, blood glucose, total cholesterol concentration in women. Abnormalities found in the middle-aged subjects were also the case with relatively young subjects. The results indicate that daily habits such as alcohol intake, calory intake, and so on, were important in the control of blood pressures. Intervention trial may be necessory to prevent hypertension and its complications. (Journal of Health Science. Kyushu University. 10: 1-7 1988)続きを見る
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