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24時間尿中Na排泄量推定法に関する研究 : 尿中クレアチニン排泄量予測値と分割尿を用いた推定法の基礎的検討

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概要 The study was undertaken to estimate 24-hour sodium excretion in urine from Na/Creatinine (Na/Cr) ratio in fractional urine and creatinine excretion in urine predicted from age, body height and body w...eight by multiple regression analysis. Three hundred and thirtyfour clinically healthy subjects (174 men and 160 women), aged from 18 to 77 years, were contributed to the study. They were asked to collect 4-hour fractional urine for ensuing 24 hours. The correlations were determined between 24-hour urinary Na/Cr ratio and 0400-0800h, 0800-1200h, 1200-1600h or OOO0-0800h fractional urine Na/Cr (FUNa/Cr) ratio, respectively. They were all closely correlated with 24-h UNa/Cr ratio (24HUNa/Cr). Estimated Na excretion calculated from the form (FUNa/Cr×predicted creatinine) for each fractional urine were closely correlated with 24HUNa, the highest correlation coefficient being 0.784 for 1200-1600h urine. The estimated value for 24HUNa (Y) was obtained from the following equation : Y=0.513X+58.3 (X=FUNa/Cr [1200-1600h]×Predicted Cr) Y=0.422X+84.2 (X=FUNa/Cr [0800-1200h]×Predicted Cr) This method may be applied for estimating sodium intake in both epidemiological and clinical study.続きを見る

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登録日 2009.09.10
更新日 2018.08.31