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Effects of ascorbic acid on blood pressure were studied in 20 male students with borderline hypertension, using the double blind method. The subjects were divided into the two groups, one given ascorb...ic acid of 3g daily, the other given placebo, with special care to ensure that the two types of tablets were indistinguishable in color, shape and taste. During the experimental period from November to January were measured blood pressure twice a week, ascorbic acid and catecholamine concentration in plasma monthly. The results obtained were as follows ; 1) Ascorbic acid group showed significant decrease in blood pressure and increase in plasma ascorbic acid, while placebo group also revealed the same decrease in systolic pressure as ascorbic acid group, despite slight increase in plasma ascorbic acid. 2) No differences were shown in both plasma catecholamine and response for cold pressor test between ascorbic acid and placebo groups, before and after administration of ascorbic acid. These results may show that ascorbic acid has no more effect, than placebo in borderline hypertension, although slight increase of plasma ascorbic acid in the control group might influence the decrease in blood pressure in the group.続きを見る
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