||Thermoregulatory responses to cold exposure at 8℃ for 40 min were studied on male (n=6) and female (n=10) subjects. Oral and axillary temperatures, skin temperature, oxygen consumption, respiratory ra...te, and blood pressure were observed before and during cold exposure. The results were summarized as follows : 1. Oral and axillary temperatures during cold exposure decreased by 1.7℃ and 1.2℃ in male subjects, and by 1.4℃ and 0.6℃ in female subjects for 40 min, respectively. 2. All temperatures measured on various parts of the skin fell significantly, but no significant difference was observed in mean skin temperature between male and female groups. 3. Oxygen consumption increased significantly during cold exposure, 88% in male and 48% in female groups, and the increases in men compared with women were statistically significant. 4. A slight decrease in respiratory frequency during cold exposure was observed in men and women, but no significant difference between male and female groups. 5. Systolic and diastolic blood pressure during cold exposure increased in both groups, and diastolic blood pressure increased more in male subjects than in female ones. These results suggest that thermoregulatory responses to cold exposure were different between men and women.