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＜Doctoral Thesis＞
The interpolated projection data estimation method improves the image quality of myocardial perfusion SPECT with a short acquisition time.
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| Abstract | Objective The interpolated projection data estimation processing (IPDE) method increases the amount of projection data by interpolation of the projection data. We examined the usefulness of the IPDE me...thod for ^2^0^1T1 myocardial perfusion imaging (MPI) single photon emission computed tomography (SPECT) with a short acquisition time. Methods Forty patients with suspected ischemic heart disease underwent stress ^2^0^1T1-MPI SPECT. Both stress and delayed images were acquired by 4 cycles of 360° continuous rotation with a 90-direction setting for 14 min. The projection data used for reconstruction were 1) all cycle data (T1-90-14min), 2) 2 cycles of data (T1-90-7min), and 3) 2 cycles of data processed using the IPDE method (T1-180IPDE-7min). This study compared the detection of the perfusion defect by the uptake score and the image quality of ^2^0^1T1-MPI SPECT using the normalized mean square error (NMSE). Results The uptake score of T1-180IPDE-7min was significantly more concordant with T1-90-14min in comparison to the T1-90-7min (p<0.05). The NMSE of the T1-180IPDE-7 min (1.85±1.06%) was significantly lower than that of the T1-90-7min IPDE improves SPECT MPI 4 (2.07±1.24%) (p<0.05). The degree of improvement by the IPDE method was significantly greater for the delayed ^2^0^1T1-MPI SPECT than for the stress ^2^0^1T1-MPI SPECT (p<0.05). Conclusion The IPDE method improved the image quality and secured the diagnostic ability of ^2^0^1T1-MPI SPECT for a short acquisition time. Furthermore, the IPDE method is a simple software program that does not require any expensive equipment or use advanced algorithms. These results suggest the possibility that the IPDE method can be useful as a supporting method for shortening the acquisition time of ^2^0^1T1-MPI SPECT.show more |
| Table of Contents | Abstract Introduction Materials and Methods Results Discussion Conclusion Acknowledgments References |
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| Created Date | 2013.07.12 |
| Modified Date | 2023.12.08 |