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Abstract |
This research project aims to develop a new and effective catalytic asymmetric synthesis on the basis of an activation method using a chiral Lewis acid catalyst. From this viewpoint, an effective asym...metric conjugate addition reaction of electron-rich aromatic compounds to sulfonyl-functionalized enones is examined in the presence of chiral Lewis acids. Furthermore, the synthesis of a variety of optically active derivatives is also performed by the transformation of the β-keto sulfone moiety of conjugated adducts.show more
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