| Creator |
|
|
|
|
|
|
|
|
|
|
|
| Language |
|
| Publisher |
|
|
|
| Date |
|
| Source Title |
|
| Vol |
|
| Issue |
|
| First Page |
|
| Last Page |
|
| Publication Type |
|
| Access Rights |
|
| JaLC DOI |
|
| Related DOI |
|
|
|
|
|
| Related URI |
|
|
|
|
|
| Relation |
|
|
|
|
|
| Abstract |
In recent times the study of estrogens and antiestrogens, both naturally occuring and synthetic, has gained importance in such diverse but interlinked fields as the development of radiodiagnostica for... breast cancer, [1] the advancement of both chemical cancer therapy［2] and hormone replacement therapy as well as the systematic study of the action of environmental hormones on the human endocrinal system and their effect on wildlife. Although compounds that possess estrogenic or antiestrogenic character can be of a variety of structures, the natural human estrogen is the steroid estra-3,7β-diol. in the last 3 decades a l ot of research has been devoted to the development of new steroids with applications in the fields mentioned above. Especially, C7-substituted steroids have been at the forefront of that development. The following review focuses on the synthesis of C-7 substituted estrane derivatives.show more
|
Export Mendeley
KJ00004507974