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Asymptomatic viral myocarditis associated with common cold as a cause of cardiovascular accidents has been recognized. Since studies investigating electrocardiographic (ECG) manifestation observed in... such a condition are scanty, we conducted ECG and, in part, echocardiographic recordings of Kyushu University students at annual health examination in April. Catching cold or not was judged by questionnaire conducted simultaneously in the examination. Abnormal ST-T change was observed with significantly (p<0.05) higher incidence in the group of students suffering from cold (n=75) than in the control group (n=156). Incidence of other abnormal ECG findings, such as incomplete right bundle branch block, atrioventricular block, premature beats, left ventricular overload, was the same in the two groups. ST-T abnormality was not associated with left ventricular high voltage (Sv1+Rv5), female dominancy, tachycardia or the incidence of mitral valve prolapse syndrome. Pericardial effusion was not detected in all students. Furthermore, ST-T abnormality was normalized at the 2 month follow-up study in June, when common cold was disappeared. These results suggest that this reversible ST-T abnormality was not the nonspecific ST-T change based on the juvenile or strain pattern, but the repolarization abnormality caused by the myocardial damage based on the self-limited, subclinical viral myocarditis associated with common cold.show more
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