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Total Synthesis of Biologically-active Terpenoids

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Abstract Starting from the C_<10>-synthon (an iridoid derivative), obtained from the de Mayo reaction of methyl acetopyruvate and isoprene, several biologically-active terpenoids have been synthesized stereose...lectively. Some new synthetic methodologies, such as the lactol-regulated Cope rearrangement and the kinetically-controlled dissolving metal reduction, are also described.show more

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Created Date 2009.04.22
Modified Date 2020.10.09

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