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The term "Hashimoto's thyroiditis" is best reserved for the patient with a diffuse and/or multinodular goiter and evidence of an autoimmune process. Patients with this disease usually may maintain nor...mal thyroid function for this lifetime. However, approximately fifty per cent of patients progress to overt hypothyroidism. In severe hypothyroidism patients have thicked, dry, flaking skin-termed "myxedema". The clinical state of hypothyroidism is manifest in all organ system. These manifestations are to large extent independent of the underlying disorder in the thyroid gland, but are more closely related to the degree of hormone deficiency. The symptoms of this disease are non-specific and may be attributed by both patient and doctor to ageing; the onset usually being insidious. We described in this report clinical signs and symptoms of primary hypothyroidism based upon our experienced cases due to Hashimoto's thyroiditis.show more
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