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There is an increasing use of ambulatory blood pressure (BP) monitoring for the clinical diagnosis of arterial hypertension. The BP monitoring is still analyzed with reference to fixed limits. This di...agnostic method is highly improved by the use of temporal criteria according to a methodology which is called "chronodiagnosis" of arterial hypertension. The chronodiagnostic procedure is structured in three levels, each one providing a specific assessment of BP 24-h pattern. Level 1 analyses the discrete variability of BP raw values. Level 2 estimates the periodic component of BP 24-h pattern which is physiologically arranged to fluctuate with a circadian rhythm. Level 3 computes measures on the BP 24-h pattern as a "whole" in order to estimate the Baric Impact produced by the circadian oscillation. According to the chronodiagnostic procedure arterial hypertension can be qualified in its excess and temporal duration. The chronobiometric approach to BP monitoring provides, thus, 1, a more accurate diagnosis; 2. a clinical estimate of the tensiogenic regimen, 3. a clinical classification of arterial hypertension into definite chronopathologic types.show more
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