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The present study has been undertaken aiming at the elucidation of the effects of aging and endurance training on enzyme activities of skeletal muscles in rat hindlimb. The slow soleus and the fast ex...tensor digitorum longus (EDL) were obtained from Fischer strain rats. These muscles were used for the determination of phosphofructokinase (PFK) activity and succinic dehydrogenese (SDH) activity. Method of endurance training used in this study was treadmill running. Training groups were forced to running training on a treadmill 5 days per week for 8 weeks from aged 10 (young), 65,79 (middle) and 107 (old) weeds after birth. The results are summarized as follows: 1. Maximal activities of PFK and SDH in soleus and EDL were obtained at 18 weeks old, and activities of these enzymes dropped with aging gradually. 2. Activities of PFK and SDH in both muscles were significantly higher after endurance training in young, middle and old rats. It is concluded that the properties of PFK and SDH activities in rat skeletal muscle are influenced by aging, however, these enzyme activities of muscles significantly increased after endurance training in young, middle and old rats.show more
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