Analysis of Stereochemical Stability of Dynamic Chiral Molecules using an Automated Microflow Measurement System - Collections | Kyushu University Library

＜journal article＞
Analysis of Stereochemical Stability of Dynamic Chiral Molecules using an Automated Microflow Measurement System

Creator	Author PID K003109 80401529 0000-0002-7354-5162 Creator Name Igawa, Kazunobu 井川, 和宣イガワ, カズノブ Affiliation Affiliation Name Institute for Materials Chemistry and Engineering, IRCCS 統合物質創製化学研究推進機構九州大学先導物質化学研究所 Affiliation Affiliation Name Department of Molecular and Material Sciences, Kyushu University 九州大学大学院総合理工研究院
	Author PID K007131 30827522 0000-0001-6297-057X Creator Name Asano, Shusaku 浅野, 周作アサノ, シュウサク Affiliation Affiliation Name Institute for Materials Chemistry and Engineering, IRCCS 統合物質創製化学研究推進機構九州大学先導物質化学研究所
	Creator Name Yoshida, Yuki ヨシダ, ユキ Affiliation Affiliation Name Department of Molecular and Material Sciences, Kyushu University 九州大学大学院総合理工学府物質理工学専攻
	Author PID K006223 00781999 0000-0003-3354-1690 Creator Name Kawasaki, Yuuya 河崎, 悠也カワサキ, ユウヤ Affiliation Affiliation Name Institute for Materials Chemistry and Engineering, IRCCS 統合物質創製化学研究推進機構九州大学先導物質化学研究所
	Author PID K003087 70207629 0000-0002-0762-5746 Creator Name Tomooka, Katsuhiko 友岡, 克彦トモオカ, カツヒコ Affiliation Affiliation Name Institute for Materials Chemistry and Engineering, IRCCS 統合物質創製化学研究推進機構九州大学先導物質化学研究所 Affiliation Affiliation Name Department of Molecular and Material Sciences, Kyushu University 九州大学大学院総合理工研究院
Language	English
Publisher	American Chemical Society
Date	2021-07-16
Source Title	The Journal of Organic Chemistry
Vol	86
Issue	14
First Page	9651
Last Page	9657
Publication Type	Accepted Manuscript
Access Rights	open access
Related DOI	isVersionOf https://doi.org/10.1021/acs.joc.1c00914


Abstract	An automated microflow measurement system for the kinetic study of racemization of dynamic chiral molecules was developed. This system facilitated the analysis of fast racemization within several seco...nds at elevated temperatures owing to its rapid heating ability, high performance for controlling short residence times, and ease of connection to HPLC systems for direct measurement of the enantiomeric purity. A more precise analysis was realized by combination of microflow and common batch measurements over a broad range of temperatures.show more

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PISSN	0022-3263
EISSN	1520-6904
NCID	AA12097242
Record ID	4785224
Related PubMed ID	34232638
Type	Article
Funding Information	Funder Name Japan Society for the Promotion of Science (JSPS) 日本学術振興会 Award Number 20H02743 Award Title キラルケイ素分子の精密合成法開発と新規生物活性分子創製への展開
	Funder Name Japan Society for the Promotion of Science (JSPS) 日本学術振興会 Award Number 20H05677 Award Title Development of DYASIN: Novel Approach to Enantioenriched Chiral Molecules キラル分子を光学活性体として得る革新的手法DYASINの開発
	Funder Name Japan Society for the Promotion of Science (JSPS) 日本学術振興会 Award Number 20K15081 Award Title Understanding deactivation mechanism of homogeneous catalyst by using micro flow reactor and automated experiments フローリアクターと自動実験の活用による錯体触媒失活機構の解明
	Funder Name Network Joint Research Center for Materials and Devices 物質・デバイス領域共同研究拠点
Created Date	2022.05.26
Modified Date	2022.07.19