Export Mendeley
＜departmental bulletin paper＞
Studies on Sodium Transport in Human Red Blood Cells.
| Creator | |
|---|---|
| Language | |
| Publisher | |
| Date | |
| Source Title | |
| Vol | |
| First Page | |
| Last Page | |
| Publication Type | |
| Access Rights | |
| JaLC DOI | |
| Related DOI | |
| Related URI | |
| Relation | |
| Abstract | Na-influx in red cells was measured in normotensive and borderline hypertensive subjects using the Mahoney's method. In normotensives, Na-influx was higher in males than in females, and also in offspr...ing of hypertensives than in those without familial predisposition of hypertension, compared between age-matched groups. Influence of age on Na-influx was unclear in both sex groups. In male subjects, Na-influx showed higher values in 14 borderline hypertensives than in 12 normotensives, and also higher in 9 women with high normal blood pressure (Hi-BP) than in 12 women with low normal blood pressure (Lo-BP). To test the effect of Na and K intake on Nainflux, Hi-BP and Lo-BP groups were given 200-220 mEq of Na and 40-50 mEq of K one by one, in addition to a normal intake of 100-120 mEq Na and 40-50 mEq K per day. Na load significantly increased Na-influx in Hi-BP group, but did not in Lo-BP group. On the other hand K load insignificantly decreased Na-influx in Lo-BP group, but unchanged in Hi-Bp group. In young men, Na-influx from 21 borderline hypertensives was statistically significantly increased after one-hour upright position, whereas that from 12 normotensives unchanged. Responsibility of Na-influx to upright position was not significantly correlated with blood pressure in either group. In order to investigate the mechanism of changes in Na-influx, variables other than blood pressure should be taken into account. Six healthy women, 22 years of age, stayed in RISM (Rational Intensive Self Measurement) rooms, Kyushu University for 3 days seasonally. Four-hourly blood sampling revealed circadian variation of Na-influx. Its peak appeared at around midnight. No report has been made on circadian rhythm of Na-influx. Its detection and explanation remain to be resolved. When we assess Na transport in cell membrane, conditions such as sampling time, position and Na intake should be considered.show more |
| Table of Contents | はじめに 測定方法 対象と方法 結果 考按 結語 文献 |
Hide fulltext details.
| File | FileType | Size | Views | Description |
|---|---|---|---|---|
007_p043
|
387 KB | 154 |
Details
| Record ID | |
|---|---|
| Peer-Reviewed | |
| Spatial | |
| ISSN | |
| NCID | |
| Type | |
| Temporal | |
| Created Date | 2009.09.10 |
| Modified Date | 2022.02.10 |