About 60 pseudopurine and guanidino-pyrimidine derivatives were scrutinized for the effects on the seedling growth of rice, radish, barnyard grass, and Atriplex gmelinii. It was found that 5-thiocyano and 5-methylthio derivatives of triazolo [l, 5-a] pyrimidine derivatives (A) inhibited strongly the growth of the root of the rice seedling. As compounds repressing leaves and stalks, some derivatives of thiadiazolo [3,2-a] pyrimidine(B) were found. 2-Thioacetic acid derivative of (A), 2-thiobenzyl, and alkanesulfinyl derivatives of (B) inhibited markedly barnyard grass, but not rice. On the other hand, compound 15 and 48 inhibited only the germination of radish.