Dietary Effect of Soybean Extrancts on Lipid Metabolism and Immune Function of Sprague-Dawley Rats - Collections | Kyushu University Library

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＜departmental bulletin paper＞
Dietary Effect of Soybean Extrancts on Lipid Metabolism and Immune Function of Sprague-Dawley Rats

Creator	Creator Name 岡本, 威明 Okamoto, Takeaki Affiliation Affiliation Name 九州大学大学院生物資源環境科学府生物機能科学専攻生物機能化学講座食糧化学研究室 Laboratory of Food Chemistry, Division of Bioscience and Biotechnology, Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University
	Creator Name 吉見, 一真 Yoshimi, Kazuma Affiliation Affiliation Name 九州大学大学院生物資源環境科学府生物機能科学専攻生物機能化学講座食糧化学研究室 Laboratory of Food Chemistry, Division of Bioscience and Biotechnology, Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University
	Creator Name 東條, 直己 Tojo, Naomi Affiliation Affiliation Name Program of Food Chemistry, Course of Applied Biological Science, Department of Bioresource and ioenvironment, School of Agriculture, Kyushu University
	Creator Name 安田, 伸 Affiliation Affiliation Name 九州大学大学院生物資源環境科学府生物機能科学専攻生物機能化学講座食糧化学研究室
	Creator Name 服部, 絵美 Affiliation Affiliation Name 九州大学農学部生物資源環境学科応用生物科学コース食糧化学工学分野
	Author PID K001607 Creator Name 立花, 宏文 Tachibana, Hirofumi Affiliation Affiliation Name 九州大学大学院生物資源環境科学府生物機能科学専攻生物機能化学講座食糧化学研究室 Laboratory of Food Chemistry, Division of Bioscience and Biotechnology, Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University
	Author PID K000847 Creator Name 山田, 耕路 Yamada, Koji Affiliation Affiliation Name 九州大学大学院生物資源環境科学府生物機能科学専攻生物機能化学講座食糧化学研究室 Laboratory of Food Chemistry, Division of Bioscience and Biotechnology, Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University
Language	Japanese
Publisher	九州大学大学院農学研究院
Publisher	Faculty of Agriculture, Kyushu University
Date	2002-10
Source Title	Science bulletin of the Faculty of Agriculture, Kyushu University
Vol	57
Issue	1
First Page	27
Last Page	34
Publication Type	Version of Record
Access Rights	open access
JaLC DOI	https://doi.org/10.15017/21119

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PISSN	1347-0159
NCID	AA11577672
Record ID	21119
Peer-Reviewed	Unrefereed
Subject Terms	Sprague-Dawley系ラット
	大豆抽出物
	脂質代謝
	免疫機能
	摂食効果
	大豆ホモジェネート摂食群
Notes	To clarify the lipid metabolism and immune function of soybean extracts, Sprague-Dawley rats were fed diets with sample powders containing 3％ level. After soybean homogenate was fed to rats for 3 weeks, IgG productivity of spleen lymphocytes was enhanced and HDL-Chol level for T-Chol level in serum was increased. The immunoglobulin production stimulating effects by soybean homogenate may be useful for activation of host defenses. On the other hand, feeding of enzyme digested soybean homogenate decreased GOT and GPT activities in serum. These results suggested that enzyme digested soybean homogenate may be prevention against lesion of hepatic function. In this study, it is clear that soybean hornogenate and digestive products have novel biological and physiological regulatory function.
Notes	大豆抽出物の脂質代謝および免疫機能を明らかにするために，それらのサンプルを食餌重量に対し3％レベルでSprague-Dawley系ラットに摂食させた．その結果　大豆ホモジェネート摂食群において，全身免疫系に属する脾臓リンパ球のIgG抗体生産能の増強効果および血清中のT-Cholに対するHDL-Cholの割合の上昇が認められた．これにより，大豆ホモジェネート摂食による抗体産生促進作用は宿主免疫の活性化に有用である可能性が期待された．一方，酵素処理大豆ホモジェネート摂食により，GOTおよびGPT活性が減少することより肝機能障害予防効果が期待された．本研究により，大豆ホモジェネートおよび大豆ホモジェネートから派生する分解物の新規生理機能が明らかとなった．
Created Date	2012.07.26
Modified Date	2022.11.11