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Abstract |
Breath analysis technique using small and inexpensive electronic devices provide a great potential to monitor a daily health condition and diagnose serious diseases at early stage due to its simplicit...y and non-invasiveness unlike conventional blood and/or urine test. However, discriminating the volatile molecule compounds (VOCs) contained in human breath is quite difficult by using electronic sensor devices since there are over 870 VOCs species in human breath and some molecules are structurally and chemically similar. Here we demonstrate the pre-discrimination technique for structurally and chemically similar VOCs via physical/chemical interactions with ZnO nanowire surface. We found that nonanone (C9) molecules with different intramolecular ketone group position exhibit the different desorption temperature which is caused by an adsorbed molecule conformation induced chemical interaction on ZnO nanowire surface. Our discovery provides a platform to discriminate the various kinds of VOCs by combining the oxide nanowire device with electronic sensor devices.show more
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