Estimation of proton density fat fraction of the salivary gland - 九大コレクション | 九州大学附属図書館

＜学術雑誌論文＞
Estimation of proton density fat fraction of the salivary gland

作成者	著者識別子 10295090 0000-0002-3457-7719 作成者名 Chikui, Toru 筑井, 徹チクイ, トオル所属機関所属機関名 Department of Oral and Maxillofacial Radiology, Faculty of Dental Science, Kyushu University 九州大学大学院歯学研究院口腔顎顔面病態学口腔画像情報科学分野
	著者識別子 70380516 作成者名 Yamashita, Yasuo 山下, 泰生ヤマシタ, ヤスオ所属機関所属機関名 Department of Medical Technology, Kyushu University Hospital 九州大学病院
	著者識別子 30513197 作成者名 Kise, Yoshitaka 木瀬, 祥貴キセ, ヨシタカ所属機関所属機関名 Department of Oral and Maxillofacial Radiology, School of Dentistry, Aichi Gakuin University 愛知学院大学
	作成者名 Saito, Tomonori 齊藤, 朋典サイトウ, トモノリ所属機関所属機関名 Department of Medical Technology, Kyushu University Hospital 九州大学病院
	著者識別子 20346802 作成者名 Okamura, Kazutoshi 岡村, 和俊オカムラ, カズトシ所属機関所属機関名 Department of Oral and Maxillofacial Radiology, Faculty of Dental Science, Kyushu University 九州大学大学院歯学研究院口腔顎顔面病態学口腔画像情報科学分野
	著者識別子 20210643 作成者名 Yoshiura, Kazunori 吉浦, 一紀ヨシウラ, カズノリ所属機関所属機関名 Department of Oral and Maxillofacial Radiology, Faculty of Dental Science, Kyushu University 九州大学大学院歯学研究院口腔顎顔面病態学口腔画像情報科学分野
本文言語	英語
出版者	Oxford University Press (OUP)
発行日	2018-02-06
収録物名	The British Journal of Radiology
巻	91
号	1085
開始ページ	20170671
アクセス権	metadata only access
権利関係	Public access to the fulltext file is restricted by copyright reason.
権利関係	著作権処理未完了のため本文ファイル非公開
関連DOI	https://doi.org/10.1259/bjr.20170671
関連URI
概要	Objective: Our first objective was to prove the validity of the six-point Dixon method for estimating the proton density fat fraction (PDFF) of the salivary gland. The second objective was to estimate ...the salivary gland PDFF using Dixon method to evaluate the pathological conditions. Methods: At first, 12 volunteers underwent two types of sequences: single-voxel magnetic resonance spectroscopy and the Dixon method and the PDFFs obtained by the two methods were compared. Next, a total of 67 individuals [normal, n = 46; Sjögren’s syndrome (SS), n = 11; and IgG4-related dacryoadenitis and sialadenitis (IgG4-DS), n = 4, parotitis, n = 6] were enrolled to estimate the parotid gland (PG) and submandibular gland (SMG) PDFF using the Dixon method. Results: This volunteer study demonstrated excellent correlation between two methods (R^2 = 0.964, slope = 1.05). In the normal group, the PG-PDFF was correlated with the weight and body mass index (BMI) (ρ = 0.38, p = 0.0085; and ρ = 0.63, p < 0.0001). The SMG-PDFF was also correlated with the weight, BMI, and serum triglyceride (ρ = 0.37, p = 0.0067; ρ = 0.42, p = 0.0022; and ρ = 0.35, p = 0.024). The PG-PDFF of the SS group (48.2 ± 15.1%) was higher than that of any other groups; however, no significant difference was found due to the wide overlap. The SS group (39.0 ± 26.14%) also had significantly higher SMG-PDFF than the normal group (8.9 ± 5.4%), p < 0.0001) and IgG4-DS group (3.8 ± 2.3%), p = 0.020). Conclusion: The Dixon method is a feasible method for estimating the PDFF and demonstrates fat accumulation in SMG in the SS group. Advances in knowledge: The PDFF obtained by the Dixon method is helpful for understanding the salivary gland pathological condition.続きを見る

詳細

PISSN	0007-1285
EISSN	1748-880X
NCID	AA00575096
レコードID	7218266
主題	Head and Neck
タイプ	Journal Article
助成情報	助成機関名 Ministry of Education, Culture, Sports, Science and Techonology-Japan 文部科学省研究課題番号 15K11073 研究課題名 Application of Amide proton transfer imaging to the orofacial region 顎顔面部における可動性蛋白質/ペプチドの化学交換イメージングの検討
登録日	2024.08.08
更新日	2024.08.08