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Understanding the deposition of inhaled toxic particles is critical in evaluating numerous health risks, especially in the lower airway. Recently, the computational fluid dynamics (CFD) method has bee...n introduced as a promising method to facilitate the accurate prediction of airflow and particle behavior in complex geometry. Therefore, this study applied the CFD method to investigate the deposition characteristic of fine particles in the human respiratory tract from the nostrils to the 7th generation. The airflow pattern was simulated using the Eulerian method at breathing flow rates of 7.5 and 30 L/min, and was followed by particle (aerodynamic diameter 1 to 10μm) deposition simulation using the Lagrangian method. In general, the results were comparable with experimental data. The high deposited concentration of particles was found at the 5-7th generation, and a specific deposition hot-spot was observed at the carina ridge.続きを見る
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