The hydrolysis of 2-phenyl-4,5-(D-glucopyrano)-Δ^2- oxazoline was studied at various pHs. The pH-logk profile showed that the apparent pK value of the oxazoline was 3. It was found that the hydrolyzed products of oxazoline in acid and neutral region were the amide. In addition to lyate species, catalytic activities of imidazole, acetic acid and Tris(hydroxymethy1) aminomethane for hydrolysis of the sugar oxazoline were examined. However, no effects were observed with these compounds. The mechanism of lysozyme catalysis was discussed on the basis of the expermiental results.
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