<図書>
Cytokines in human health : immunotoxicology, pathology, and therapeutic applications
責任表示 | edited by Robert V. House, Jacques Descotes |
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シリーズ | Methods in pharmacology and toxicology / Mannfred A. Hollinger, series editor |
データ種別 | 図書 |
出版情報 | Totowa, NJ : Humana Press , c2007 |
本文言語 | 英語 |
大きさ | x, 366 p. ; 24 cm |
概要 | Cytokines in Human Health: Immunotoxicology, Pathology, and Therapeutic Applications explores the role of cytokines in immunotoxicology and human health by using a variety of complex biological method..., ranging from basic bench research all the way through highly applied therapeutic applications. The first section of the book is devoted to basic concepts of cytokine biology, especially in its relation to the practice of immunotoxicology. Chapters in this section review external influences ability to modify the expression, production, and activity of these molecules. The second section provides a broad understanding of the range of cytokine activity in human disease, describing methods for assessing cytokine immunotoxicity. In the third and final section of the book, the increasingly important use of cytokines as therapeutics is explored in detail. This section includes examinations into the effects of cytokines on the immune system and in the treatment of cancer. Timely and comprehensive, Cytokines in Human Health: Immunotoxicology, Pathology, and Therapeutic Applications serves as both a primer and a starting point for a more detailed investigation of the role these fascinating biological regulators play in human health and disease. Features: Provides insights into basic research techniques and applied therapeutic applications, Includes a basic study of cytokines, Details the effects of cytokines on the immune system and in treating cancer. Book jacket.続きを見る |
目次 | Introduction to cytokines as targets for immunomodulation / Theresa Whiteside Cytokine measurement tools for immunotoxicology / Rob J. Vandebriel The relevance of the T1/T2 paradigm in immunotoxicology: example of drug hypersensitivity reactions / Herve Lebrec and John Vasilakos Microbial exploitation and subversion of the human chemokine network / James Pease The use of cytokines in the identification and characterization of chemical allergens / Rebecca Dearman and Ian Kimber Inflammatory cytokines and lung toxicity / Debra L. Laskin ... [et al.] Cytokine polymorphisms and relationship to disease / Berran Yucesoy ... [et al.] Effects of drugs of abuse on cytokine responses / Stephen B. Pruett Preclinical approaches for safety assessment of cytokines / Peter T. Thomas and Melissa S. Beck-Westermeyer The flu-like syndrome and cytokines / Jacques Descotes and Thierry Vial Cytokine-induced vascular leak syndrome / Roxana Baluna Cytokines and autoimmune diseases: from the control of autoimmune diseases with anti-cytokine treatment to the induction of autoimmunity with cytokine treatment / Pierre Miossec Evaluation of antibodies in clinical trials of cytokines / Steven Swanson Cytokines and pharmacokinetic drug interactions / Kenneth Renton Evaluation of the immunological effects of cytokines administered to patients with cancer / Michael Robertson Clinical adverse effects of cytokines on the immune system / Thierry Vial and Jacques Descotes.続きを見る |
電子版へのリンク | https://hdl.handle.net/2324/6982056 |
所蔵情報
状態 | 巻次 | 所蔵場所 | 請求記号 | 刷年 | 文庫名称 | 資料番号 | コメント | 予約・取寄 | 複写申込 | 自動書庫 |
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筑紫図 1D 450-599 | 491.8/H 91 | 2007 |
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067212007000100 |
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書誌詳細
一般注記 | Includes bibliographical references and index |
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著者標目 | House, Robert V. Descotes, Jacques, 1925- |
件 名 | LCSH:Cytokines LCSH:Immunotoxicology MESH:Cytokines -- immunology 全ての件名で検索 MESH:Cytokines -- therapeutic use 全ての件名で検索 |
分 類 | LCC:QR185.8.C95 NLM:QW 568 DC22:616.07/9 |
書誌ID | 1001334591 |
ISBN | 9781588294678 |
NCID | BA82237333 |
巻冊次 | ISBN:9781588294678 ; XISBN:1588294676 |
登録日 | 2009.09.18 |
更新日 | 2017.02.18 |