Statistical mechanics and stability of macromolecules : application to bond disruption, base pair separation, melting, and drug dissociation of the DNA double helix

＜図書＞
Statistical mechanics and stability of macromolecules : application to bond disruption, base pair separation, melting, and drug dissociation of the DNA double helix

責任表示	Earl Prohofsky
データ種別	図書
出版情報	Cambridge, Eng. ; New York : Cambridge University Press , 1995
本文言語	英語
大きさ	x, 227 p. : ill. ; 24 cm
概要	Develops a statistical mechanical analysis of the stability of biological macromolecules that is valid both for the long time scale needed for DNA bond disruption and for the highly cooperative transi...ions needed to explain helix melting. Devises a method for describing chemical bond disruption in such systems, and uses that to determine when the helix melts and how drugs can dissociate from the helix. Then shows how to account for environmental variables and how to perform calculations on specific structures embedded in a large helix and on the dynamic effects of enzyme attachments. For researchers and graduate students in biological physics, theoretical chemistry, and molecular biology. Annotation c. by Book News, Inc., Portland, Or.続きを見る

状態	巻次	所蔵場所	請求記号	刷年	文庫名称	資料番号	コメント	予約・取寄	複写申込	自動書庫
		医学図 3F 保存・図書	QU 58/P 964/1995	1995		042212004001275		予約・取寄			予約・取寄

一般注記	Includes bibliographical references and index
著者標目	*Prohofsky, Earl
件　名	LCSH:DNA -- Stability -- Statistical methods 全ての件名で検索 LCSH:Macromolecules -- Stability -- Statistical methods 全ての件名で検索 LCSH:Statistical mechanics
分　類	LCC:QP624.5.S73 DC20:574.87/3282
書誌ID	1000956617
ISBN	0521451841
NCID	BA25872726
巻冊次	ISBN:0521451841
登録日	2009.09.16
更新日	2009.09.16