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<図書>
Annual review of pharmacology and toxicology

責任表示 Robert George, Ronald Okun, coeditors ; Arthur K. Cho, associate editor
データ種別 図書
出版情報 Palo Alto : Annual Reviews , <19- >
本文言語 英語
大きさ v. ; 23 cm
概要 This collection of 17 articles includes a variety of topics, such as how peroxisome proliferator-activate receptors' affects on microphages can lead to the development of a new drug therapy against at...erosclerosis, cytochrome P450 and xenobiotic receptor humanized mice, human flavin-containing monooxygenases, cannabinoid receptors as therapeutic targets, regulation of drug-metabolizing enzymes and transporters in inflammation, accessory proteins for G proteins as partners in signaling, the proteasome and proteasome inhibitors in cancer, nuclear and mitochondrial compartmentalization of oxidative stress and redox signaling, the regulation and pharmacology of endothelial nitric oxide synthase, regulation of platelet function by P2 receptors, functional imaging of tumor proteolysis, the pharmacogenomics of acute leukemia, regulation of phospholipase C isozymes by the Ras superfamily, the role of ABCG2/BCRP in biology and medicine, CO as a cellular signaling molecule, the function of retinoid nuclear receptors, and the molecular mechanism of 7TM receptor activation. This issue includes related articles from the annual reviews for biochemistry, medicine, neuroscience and physiology. Annotation ©2006 Book News, Inc., Portland, OR (booknews.com)
Nineteen contributions discuss such topics as: signal transduction in environmental neurotoxicity; interactions between hormones and chemicals in breast cancer; growth hormone as therapy for older men and women; predictive value of in vitro model systems in toxicology; neuronal injury associated with HIV-1; cannabinoid receptors and their endogenous agonists; presynaptic receptors; mechanisms of action of biophosphates; the role of organic cation transporters in drug absorption and elimination; and glutathione-dependent bioactivation of haloalkenes. Annotation copyrighted by Book News, Inc., Portland, OR
Papers detail research and findings surrounding advances in the field. Topics include regulation and role in drug metabolism of cytochrome P- 450 3A4, molecular and pharmacologic regulation of the pineal gland, regulation of gene expression by reactive oxygen, cytotoxicity of short-chain alcohols, glial cells in neurotoxicity development, and regulation and inhibition of phospholipase A2. Other subjects include inhibition of nitric oxide synthase as a potential therapeutic target, genetic regulation of glutamate receptor ion channels, and teratology of retinoids. Annotation copyrighted by Book News, Inc., Portland, OR
This collection of 17 articles includes a variety of topics, such as how peroxisome proliferator-activate receptors' affects on microphages can lead to the development of a new drug therapy against atherosclerosis, cytochrome P450 and xenobiotic receptor humanized mice, human flavin-containing monooxygenases, cannabinoid receptors as therapeutic targets, regulation of drug-metabolizing enzymes and transporters in inflammation, accessory proteins for G proteins as partners in signaling, the proteasome and proteasome inhibitors in cancer, nuclear and mitochondrial compartmentalization of oxidative stress and redox signaling, the regulation and pharmacology of endothelial nitric oxide synthase, regulation of platelet function by P2 receptors, functional imaging of tumor proteolysis, the pharmacogenomics of acute leukemia, regulation of phospholipase C isozymes by the Ras superfamily, the role of ABCG2/BCRP in biology and medicine, CO as a cellular signaling molecule, the function of retinoid nuclear receptors, and the molecular mechanism of 7TM receptor activation. This issue includes related articles from the annual reviews for biochemistry, medicine, neuroscience and physiology. Annotation ©2006 Book News, Inc., Portland, OR (booknews.com)
These 33 papers concentrate on the intersection of the two disciplines. Perspectives from chemistry and biology are of course highlighted. Topics include: anesthetics and ion channels, topoisomerase-targeting drugs, L-arginine, pharmacogenomics, adenylyl cyclase isoforms, nonpeptide vasopressin receptor antagonists, nitric oxide, thioredoxins, biomarkers and surrogate endpoints, DNA damage, antisense oligonucleotides, chemoprevention, lyphospholipid receptors, prostanoid receptors, osteopontin, lithium action, ethnic differences in drug disposition, endothelin system, and neurokinin receptor antagonists. c. Book News Inc.
Twenty-three papers reflect the current state of and recent developments in pharmacology and toxicology. Topics include: the use of tea, colon cancer prevention, therapies for asthma, biotechnology and food, biomedical informatics, molecular psychology, schizophrenia, environmentally induced birth defects, AKAP-medicated signal transduction, the repression of apoptosis, glycopeptide antibiotic resistance, altered DNA methylation, and the biochemistry and physiology of S-nitrosothiols. An abstract is provided for each chapter. Annotation copyrighted by Book News Inc., Portland, OR.
Twenty-five articles represent the current state of the field, with attention to topics like: drug-metabolizing enzymes, protein flexibility, retinoid receptors, nitric oxide-related drugs, signal transduction-directed cancer treatments, genetic polymorphisms, trafficking of NMDA receptors, telomere inhibition and disruption, adrenergic receptor polymorpisms, gene therapy with viral vectors, drug-induced QT prolongation, Alzheimer's disease, and the blood- brain barrier. Numerous graphics, both black-and-white and color, illustrate various aspects of the instruction. Annotation (c)2003 Book News, Inc., Portland, OR (booknews.com)
The 2004 edition of the annual review consists of 23 papers that assess in vitro and in silico approaches to predicting drug glucuronidation parameters, methods for identifying ligands at orphan G-protein coupled receptors, and some chemicals shown to cause morphological changes in the developing nervous system. The contributors also present recent research on organic anion and peptide transporters for renal drug elimination, the major steps in botulinum toxin action, the role of oxidative stress in carcinogenesis, the potential of endogenous neural stem cells in CNS repair, and the biologic and molecular basis for sex-related disparities in pharmacokinetics and pharmacodynamics. Annotation ©2004 Book News, Inc., Portland, OR (booknews.com)
The 2005 edition of the annual volume describes studies that led to the resolution and reconstitution of the cytochrome P450 enzyme system in microsomal membranes, putative pharmacological strategies aiming at modulation of afferent and efferent fat cell messages, anecdotal and literature reports of adverse drug events with herbal products, and the targets of current tuberculosis drugs. Other topics of the 29 papers include the three mammalian glutathione transferase families, the clinical development of histone deacetylase inhibitors, the molecular mechanisms of hepatic fibrosis, and signaling networks in living cells. Each article provides detailed listings of references cited. Annotation ©2004 Book News, Inc., Portland, OR (booknews.com)
This collection of 17 articles includes a variety of topics, such as how peroxisome proliferator-activate receptors' affects on microphages can lead to the development of a new drug therapy against atherosclerosis, cytochrome P450 and xenobiotic receptor humanized mice, human flavin-containing monooxygenases, cannabinoid receptors as therapeutic targets, regulation of drug-metabolizing enzymes and transporters in inflammation, accessory proteins for G proteins as partners in signaling, the proteasome and proteasome inhibitors in cancer, nuclear and mitochondrial compartmentalization of oxidative stress and redox signaling, the regulation and pharmacology of endothelial nitric oxide synthase, regulation of platelet function by P2 receptors, functional imaging of tumor proteolysis, the pharmacogenomics of acute leukemia, regulation of phospholipase C isozymes by the Ras superfamily, the role of ABCG2/BCRP in biology and medicine, CO as a cellular signaling molecule, the function of retinoid nuclear receptors, and the molecular mechanism of 7TM receptor activation. This issue includes related articles from the annual reviews for biochemistry, medicine, neuroscience and physiology. Annotation ©2006 Book News, Inc., Portland, OR (booknews.com)
Cho (U. of California School of Medicine, Los Angeles) et al. present this 47th annual collection of current research in pharmacology and toxicology. Twenty-four articles discuss topics including: allosteric modulation of G protein-coupled receptors, AMP-activated protein kinase as a drug target, aldo-keto reductases and bioactivation/detoxication, current and future pharmacological treatments for obesity, acute effects of estrogen on neuronal physiology, new insights into the mechanism of action of amphetamines, and nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system, among others. Two indexes list authors and chapter titles from volumes 43-47. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)
The 2008 edition of the annual series summarizes recent findings on the nuclear receptors that control xenobiotic metabolism and transport, the mechanisms of placebo effects across diseases and treatments, the activation of G protein-coupled receptors, and the therapeutic potential of apoptin as an early sensor of carcinogenic transformation. Other topics of the 23 articles include the role of CYP1B1 in glaucoma, biomarkers of acute kidney injury, PKC isozymes in chronic cardiac disease, and the metabolomics approach to drug response and disease. Annotation ©2008 Book News, Inc., Portland, OR (booknews.com)
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所蔵情報


v. 16 医学図 3F 保存・図書 W 1/A 615/1976 1976
042211999000834

v. 33 芸工図 2F 書架 499.05/A49/33 1993
072032193008337

v. 43 医学図 3F 保存・図書 W 1/A 615/2003 2003
042222003000056

書誌詳細

一般注記 Includes bibliogrpphies and index
Vol. 30- Robert George, Arthur K. Cho, co-editor ; Terrence F. Blaschke, associate editor
Vol. 32,37-44,46-49:Arthur K. Cho, editor ; Terrence F. Blaschke [et al.] associate editor
著者標目 George, Robert
Okun, Ronald
Cho, Arthur K.
Blaschke, Terrence F.
件 名 MESH:Pharmacology - yearbooks
MESH:Toxicology - yearbooks
分 類 NDC8:491.5
NLM:W1
書誌ID 1000906921
ISBN 0824304160
NCID BA00313280
巻冊次 v. 13
v. 16 ; ISBN:0824304160
v. 17 ; ISBN:0824304179
v. 18 ; ISBN:0824304187
v. 19 ; ISBN:0824304195
v. 20 ; ISBN:0824304209
v. 21 ; ISBN:0824304217
v. 22 ; ISBN:0824304225
v. 23 ; ISBN:0824304233
v. 24 ; ISBN:0824304241
v. 25 ; ISBN:082430425X
v. 26 ; ISBN:0824304268
v. 27 ; ISBN:0824304276
v. 28 ; ISBN:0824304284
v. 29 ; ISBN:0824304292
v. 30 ; ISBN:0824304306
v. 31 ; ISBN:0824304314
v. 32 ; ISBN:0824304322
v. 33 ; ISBN:0824304330
v. 34 ; ISBN:0824304349
v. 35 ; ISBN:0824304357
v. 36 ; ISBN:0824304365
v. 37 ; ISBN:0824304373
v. 38 ; ISBN:0824304381
v. 39 ; ISBN:082430439X
v. 40 ; ISBN:0824304403
v. 41 ; ISBN:0824304411
v. 42 ; ISBN:082430442X
v. 43 ; ISBN:0824304438
v. 44 ; ISBN:0824304446
v. 45 ; ISBN:0824304454
v. 46 ; ISBN:0824304462
v. 47 ; ISBN:9780824304478 ; XISBN:0824304470
v. 48 ; ISBN:9780824304485
v. 49 ; ISBN:9780824304492
登録日 2009.09.16
更新日 2009.09.16

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