Top drugs : top synthetic routes

＜図書＞
Top drugs : top synthetic routes

責任表示	John Saunders
シリーズ	Oxford chemistry primers ; 90 Oxford science publications
データ種別	図書
出版情報	Oxford : Oxford University Press , 2000
本文言語	英語
大きさ	90 p. : ill. ; 25 cm
概要	Today's top selling drugs have been uncovered from two major sources: natural products and laboratory synthesis. Those synthesised directly by medicinal chemists usually have been the result of a prot...acted discovery programme using a natural product (e.g. a hormone or an enzyme substrate) or a screening lead as a starting point. Many of the major categories of human disease cardiovascular, gastrointestinal, central nervous system, inflammatory and infectious diseases are included. After a short introduction to the discovery and mechanism of action of each drug, the syntheses of the best selling drugs are reviewed. Where the information exists in the literature, the original research method to each drug is compared with more recent approaches which aim either at improving the route or at validating newer methodologies or reagents in the context of drug synthesis. Since, for many drugs, the marketed product was originally prepared as a racemic mixture, perhaps the most important comparison is between that route and alternatives which involve some element of asymmetric synthesis. 続きを見る

状態	巻次	所蔵場所	請求記号	刷年	文庫名称	資料番号	コメント	予約・取寄	複写申込	自動書庫
		筑紫図 Biblio Cookies 2階_シリーズ資料	430/O 93/90	2000		067212000005418		予約・取寄			予約・取寄
	: pbk	理系図自動書庫	430/O 93	2001		058212003001602		予約・取寄		出庫可能	予約・取寄		出庫可能

一般注記	Includes bibliographical references and index
著者標目	*Saunders, John
件　名	LCSH:Synthetic drugs
書誌ID	1000905698
ISBN	0198501005
NCID	BA47038102
巻冊次	: pbk ; ISBN:0198501005
登録日	2009.09.16
更新日	2009.11.02