<図書>
Transcriptional regulation in eukaryotes : concepts, strategies, and techniques
責任表示 | Michael Carey, Stephen T. Smale |
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データ種別 | 図書 |
出版情報 | Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory , c2000 |
本文言語 | 英語 |
大きさ | xxix, 640 p. : ill. (some col.) ; 29 cm |
概要 | After a review of the state-of-the-art in the RNA polymerase II transcription field, subsequent chapters present a systematic guide to the investigation of regulatory mechanisms for newly identified g...nes, and discuss approaches for synthesizing recombinant transcription factors, analyzing their binding, and deciphering their mode of action. Carey (UCLA) and Smale (Howard Huges Medical Institute and UCLA) write for graduate students, physician-scientists, and others, either beginning or already established, who are undertaking in-depth studies in the analysis of gene expression in model systems or disease states. They put methods in the context of underlying theory, recommend experimental strategies, encourage creativity in investigative design, and explain protocols, with troubleshooting advice. Annotation copyrighted by Book News, Inc., Portland, OR In the genome era, the analysis of gene expression has become a critical requirement in many laboratories. But there has been no comprehensive source of strategic, conceptual, and technical information to guide this often complex task. Transcriptional Regulation in Eukaryotes answers that need. Written by two experienced investigators, Michael Carey and Stephen Smale at the UCLA School of Medicine, and based in part on the Gene Expression course taught at Cold Spring Harbor Laboratory, this book directly addresses all the concerns of a laboratory studying the regulation of a newly isolated gene and the biochemistry of a new transcription factor. This important and unique book is essential reading for anyone pursuing the analysis of gene expression in model systems or disease states. 続きを見る |
所蔵情報
状態 | 巻次 | 所蔵場所 | 請求記号 | 刷年 | 文庫名称 | 資料番号 | コメント | 予約・取寄 | 複写申込 | 自動書庫 |
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医学図 3F 保存・図書 | QH 450.2/C 275/2000 | 2000 |
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042212000001485 |
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医 基礎放射線 | 2000 |
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042222000000317 |
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書誌詳細
著者標目 | Carey, Michael Smale, Stephen T. |
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書誌ID | 1000856930 |
ISBN | 0879695374 |
NCID | BA45121216 |
巻冊次 | cloth ; ISBN:0879695374 pbk. ; ISBN:0879696354 |
登録日 | 2009.09.15 |
更新日 | 2009.09.15 |