<図書>
Molecular aspects of aging : report of the Dahlem Workshop on Molecular Aspects of Aging, Berlin, 1994, 13-18 February
| 責任表示 | edited by K. Esser and G.M. Martin |
|---|---|
| シリーズ | Life sciences research report ; 56 |
| データ種別 | 図書 |
| 出版情報 | Chichester : John Wiley & Sons , c1995 |
| 本文言語 | 英語 |
| 大きさ | xv, 302 p. : ill. ; 24 cm |
| 概要 | As we approach the twenty-first century, aging is likely to emerge as a leading issue for biological and biomedical scientists. The elucidation of the underlying mechanisms of aging may constitute the...most effective approach to the prevention or postponement of major geriatric disorders. An understanding of why individual subjects vary in their susceptibilities to these disorders will be of special significance to future medicine. To further this understanding, a unique dialogue was initiated between biologists, geneticists, biochemists, pathologists, immunologists, physicians, and other biomedical scientists concerned with the molecular mechanisms of aging, which is reflected in this volume. The authors consider model systems based on yeast, simple fungi, roundworms, fruitflies, mice, and humans. They review the current status of the evolutionary theory of aging, of oxidatively modified proteins as markers of aging, the role of mitochondrial and nuclear DNA damage in aging, and the pathogenic mechanisms in common geriatric disorders such as Alzheimers disease, Parkinsons disease, atherosclerosis, and cancer. The reports summarize their debate on key issues: How can research on diverse model systems contribute to the understanding of the genetic basis of aging and longevity? Do research findings from diverse model systems support oxidative damage theories of aging? Does research on mitochondria in diverse model systems provide at least one unifying mechanism of aging? Do common underlying mechanisms of aging contribute to the pathogenesis of major geriatric disorders? Goal of this Dahlem Workshop: to examine molecular processes underlying genetic and physiological changes that occur with normal aging and geriatric disorders. 続きを見る |
所蔵情報
| 状態 | 巻次 | 所蔵場所 | 請求記号 | 刷年 | 文庫名称 | 資料番号 | コメント | 予約・取寄 | 複写申込 | 自動書庫 |
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医学図3F 洋雑誌 | 雑誌書架 | 1995 |
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042242001901907 |
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書誌詳細
| 一般注記 | Includes bibliographical references and indexes |
|---|---|
| 著者標目 | *Dahlem Workshop on Molecular Aspects of Aging (1994 : Berlin, Germany) Esser, Karl, 1924- Martin, George M., 1927- |
| 件 名 | LCSH:Aging -- Molecular aspects -- Congresses
全ての件名で検索
MESH:Aging -- genetics -- congresses 全ての件名で検索 MESH:Aging -- physiology -- congresses 全ての件名で検索 MESH:Molecular Biology -- congresses 全ての件名で検索 |
| 分 類 | LCC:QP86. NLM:W1 LI4067R v. 56 1995 NLM:WT 104 D131m 1995 DC20:574.3/72 |
| 書誌ID | 1000552614 |
| ISBN | 0471956899 |
| NCID | BA27935678 |
| 巻冊次 | ISBN:0471956899 |
| 登録日 | 2009.09.14 |
| 更新日 | 2009.09.14 |
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