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<図書>
Molecular aspects of aging : report of the Dahlem Workshop on Molecular Aspects of Aging, Berlin, 1994, 13-18 February

責任表示 edited by K. Esser and G.M. Martin
シリーズ Life sciences research report ; 56
データ種別 図書
出版情報 Chichester : John Wiley & Sons , c1995
本文言語 英語
大きさ xv, 302 p. : ill. ; 24 cm
概要 As we approach the twenty-first century, aging is likely to emerge as a leading issue for biological and biomedical scientists. The elucidation of the underlying mechanisms of aging may constitute the...most effective approach to the prevention or postponement of major geriatric disorders. An understanding of why individual subjects vary in their susceptibilities to these disorders will be of special significance to future medicine. To further this understanding, a unique dialogue was initiated between biologists, geneticists, biochemists, pathologists, immunologists, physicians, and other biomedical scientists concerned with the molecular mechanisms of aging, which is reflected in this volume. The authors consider model systems based on yeast, simple fungi, roundworms, fruitflies, mice, and humans. They review the current status of the evolutionary theory of aging, of oxidatively modified proteins as markers of aging, the role of mitochondrial and nuclear DNA damage in aging, and the pathogenic mechanisms in common geriatric disorders such as Alzheimers disease, Parkinsons disease, atherosclerosis, and cancer. The reports summarize their debate on key issues: How can research on diverse model systems contribute to the understanding of the genetic basis of aging and longevity? Do research findings from diverse model systems support oxidative damage theories of aging? Does research on mitochondria in diverse model systems provide at least one unifying mechanism of aging? Do common underlying mechanisms of aging contribute to the pathogenesis of major geriatric disorders? Goal of this Dahlem Workshop: to examine molecular processes underlying genetic and physiological changes that occur with normal aging and geriatric disorders. 続きを見る

所蔵情報



医学図3F 洋雑誌 雑誌書架 1995
042242001901907

書誌詳細

一般注記 Includes bibliographical references and indexes
著者標目 *Dahlem Workshop on Molecular Aspects of Aging (1994 : Berlin, Germany)
Esser, Karl, 1924-
Martin, George M., 1927-
件 名 LCSH:Aging -- Molecular aspects -- Congresses  全ての件名で検索
MESH:Aging -- genetics -- congresses  全ての件名で検索
MESH:Aging -- physiology -- congresses  全ての件名で検索
MESH:Molecular Biology -- congresses  全ての件名で検索
分 類 LCC:QP86.
NLM:W1 LI4067R v. 56 1995
NLM:WT 104 D131m 1995
DC20:574.3/72
書誌ID 1000552614
ISBN 0471956899
NCID BA27935678
巻冊次 ISBN:0471956899
登録日 2009.09.14
更新日 2009.09.14