<図書>
Neuronal degeneration and regeneration : from basic mechanisms to prospects for therapy
責任表示 | edited by F. Van Leeuwen ... [et al.] |
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シリーズ | Progress in brain research ; v. 117 |
データ種別 | 図書 |
出版情報 | Amsterdam : Elsevier , 1998 |
本文言語 | 英語 |
大きさ | xviii, 532 p. : ill. ; 27 cm |
概要 | This book is the result of the 20th International Summer School in Brain Research, organized in August 1997 in Amsterdam, by the Netherlands Institute for Brain Research at the Royal Netherlands Aca...emy of Sciences. It is the first book that provides a complete overview of the field of neurodegeneration and regeneration including spinal cord injury, neurodegenerative diseases and therapy. Divided into five sections, the first two sections give an overview of fundamental research on nerve cell death, neuronal survival, neurite outgrowth and guidance. Extensive attention is given to the role of neurotrophins, their receptor tyrosine kinases and cell-adhesion molecules in development and regeneration of the nervous system. The third section of the book is devoted to research involving human neurodegenerative diseases and emerging treatment strategies. Section four focusses on recent advances in the understanding of pathophysiological mechanisms underlying neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases along with prion diseases. Novel insights into the neuropathological hallmarks of these diseases, as well as into transgenic animal models, the involvement of environmental factors, and genomic and mRNA changes that can cause neurodegeneration. The final section of this volume reveals recent developments in the use of cell and gene therapy to treat neurodegenerative disease and lesion-related deficits. Implantation of genetically modified cells, direct gene transfer with viral vectors and the first clinical trials with encapsulated genetically modified cells in patients suffering from amyotrophic lateral scelerosis are examples of new therapeutic strategies treating neurodegenerative diseases. The book is of particular interest to departments of neuroscience, neurological clinics and departments, the pharmalogical industry and medical libraries. The last few years have seen a dramatic increase in the number of areas known to be involved in mammalian vision. It has also seen a far greater understanding of the importance of reciprocal connections, intrinsic connections, structure-specific modules and modules which span different structures, as well as the introduction of parallel processing models within the thalamocortical and corticocortical streams. The body of knowledge has become so vast, and is growing so rapidly, that periodic updates are essential even for experts in the field. This volume is based on a satellite meeting of an international group of researchers. It emphasizes the most current information regarding midbrain and extrastriate mechanisms underlying vision and visually-guided behavior. The book also places these data into the larger context of how interrelated components of the visual system function to produce coherent visual experiences and behavior. New research findings are presented that are unavailable elsewhere, as well as reviews and broad perspectives in which existing data from multiple sources are brought together in order to help understand the structure and function of extrageniculostriate visual areas. 続きを見る |
所蔵情報
状態 | 巻次 | 所蔵場所 | 請求記号 | 刷年 | 文庫名称 | 資料番号 | コメント | 予約・取寄 | 複写申込 | 自動書庫 |
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理系図 自動書庫 | 491.37/P 94/117 | 1998 |
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022212001000376 |
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芸工図 2F 書架 | 491.37/P94/117 | 1998 |
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072032198003965 |
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医学図3F 洋雑誌 | 雑誌書架 | 1998 |
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042241998905317 |
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書誌詳細
一般注記 | "Proceedings of the 20th International Summer School of Brain Research, held at the Royal Netherlands Academy of Sciences, Amsterdam, the Netherlands from 25 to 29 August 1997" |
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著者標目 | Leeuwen, F. W. van (Fred W.) International Summer School of Brain Reseach (20th : 1997 : Amsterdam) |
件 名 | LCSH:Nervous system -- Degeneration -- Congresses
全ての件名で検索
LCSH:Nervous system -- Regenration -- Congresses 全ての件名で検索 MESH:Nerve Degeneration congresses MESH:Nerve Regeneration congresses MESH:Neurons -- physiology congresses 全ての件名で検索 |
分 類 | LCC:QP376 LCC:RC394.D35 NLM:WL 102.5 NLM:W1 DC21:612.8/2 s DC21:616.8/047 |
書誌ID | 1000218006 |
ISBN | 0444828176 |
NCID | BA38537043 |
巻冊次 | ISBN:0444828176 series ; ISBN:0444801049 |
登録日 | 2009.09.11 |
更新日 | 2009.11.02 |