<図書>
Dopaminergic neuron transplantation in the weaver mouse model of Parkinson's disease
責任表示 | by Lazaros C. Triarhou |
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シリーズ | Advances in experimental medicine and biology ; v. 517 |
データ種別 | 図書 |
出版者 | New York : Kluwer Academic/Plenum Publishers |
出版者 | Georgetown, Tex. : Landes Bioscience |
出版年 | c2002 |
本文言語 | 英語 |
大きさ | x, 148 p. : ill. ; 26 cm |
概要 | This book is the culmination of fifteen years of research on the transplantation of dopaminergic neurons in the striatum of the weaver mouse (wv/wv), a neurological mutant characterized by geneticall...-determined degeneration of midbrain dopamine neurons. This mutant constitutes the only available laboratory model with a chronic disorder that mimics Parkinson's disease. Structural and functional aspects of intrastriatal mesencephalic neuron grafting into the weaver model are reviewed, including histochemical correlates of graft survival and integration, numerical aspects of donor cell survival, ultrastructural findings on synaptogenesis, neurochemical indices of dopamine uptake and receptor binding, gene expression of structural and neurotransmitter-receptor related molecules, levels of striatal amino acid receptors, and behavioural effects of unilateral and bilateral neuronal transplantations. 続きを見る |
所蔵情報
状態 | 巻次 | 所蔵場所 | 請求記号 | 刷年 | 文庫名称 | 資料番号 | コメント | 予約・取寄 | 複写申込 | 自動書庫 |
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医学図2F 洋雑誌 | 雑誌書架 | 2002 |
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042242003900290 |
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書誌詳細
一般注記 | Includes bibliographical references and index |
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著者標目 | *Triarhou, Lazaros Constantinos, 1957- |
件 名 | LCSH:Parkinson's disease LCSH:Dopaminergic neurons -- Transplantation 全ての件名で検索 LCSH:Parkinson's disease -- Surgery 全ての件名で検索 MESH:Parkinson Disease -- surgery 全ての件名で検索 MESH:Neurons -- transplantation 全ての件名で検索 MESH:Brain Tissue Transplantation MESH:Models, Neurological MESH:Mice, Neurologic Mutant |
分 類 | LCC:RC382 NLM:W1 NLM:WL 359 DC21:617.4/810592 |
書誌ID | 1001097557 |
ISBN | 0306474352 |
NCID | BA62073663 |
巻冊次 | ISBN:0306474352 ; XISBN:0306474182 |
登録日 | 2009.09.17 |
更新日 | 2009.09.17 |