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This study is aimed to investigate the effects of blood pressure in glucose metabolism and renin- angiotensin-aldosterone system in the young Japanese. Thirteen clinically healthy male students (21.61...± 2.3 yo, normotensive;NT, n=5, borderline hypertensive;BHT, n=8) voluntarily participated in the study. They collected urine and were taken blood, before and 1, 2, 3 hours after taking 225ml solution of 75 gram fructose. Plasma renin activity and aldosterone concentration were higher in BHT than NT. Serum glucose and glucagon concentrations were higher after fructose ingestion in BHT, suggesting their endogenous glucose production from fructose. Serum lipase concentration was lower in BHT. These results showed that even slight elevation of blood pressure influenced glucose and lipid metabolism.show more
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022_p137